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To analyze to what extent the in vitro Houses displayed by methaqualone at GABAARs correlated with its in vivo efficacy, publicity scientific tests on the drug were mixed with testing it in MEST and beam-wander assays in mice employing diazepam like a reference GABAAR modulator (Fig. 11).Overdose and deadly dose concentrations tend to be decreased

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As mentioned earlier mentioned, the negligible activity shown by methaqualone in a plethora of neurotransmitter targets inside the screening and its effects on cortical network activity while in the MEA recordings all in all seem to be to point that it is a reasonably selective GABAAR modulator (Figs.Quaaludes could be addictive, and with any chemi

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